We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Clinical trial of adjunctive celecoxib treatment in patients with major depression: a double blind and placebo controlled trial.
- Authors
Akhondzadeh, Shahin; Jafari, Sara; Raisi, Firoozeh; Nasehi, Abbas Ali; Ghoreishi, Aboulfazl; Salehi, Bahman; Mohebbi-Rasa, Soodeh; Raznahan, Maedeh; Kamalipour, Abbas
- Abstract
The pathophysiology of depression is associated with the hyperactivity of immune inflammatory responses. Cyclooxygenase-2 inhibitors such as celecoxib reduce the production of pro-inflammatory cytokines. The purpose of the present investigation was to assess the efficacy of celecoxib as an adjuvant agent in the treatment of major depression in a six-week double blind and placebo controlled trial.
- Publication
Depression and anxiety, 2009, Vol 26, Issue 7, p607
- ISSN
1520-6394
- Publication type
Journal Article
- DOI
10.1002/da.20589