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- Title
RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults.
- Authors
Koenen, Karestan C; Amstadter, Ananda B; Ruggiero, Kenneth J; Acierno, Ron; Galea, Sandro; Kilpatrick, Dean G; Gelernter, Joel
- Abstract
Generalized anxiety disorder (GAD) is a common and sometimes disabling condition often associated with stressful life events that involve significant loss or danger. The disorder appears moderately heritable. Polymorphisms in the RGS2 (regulator of G-protein signaling 2) gene were recently associated with anxious behavior in mice and panic disorder and trait anxiety in humans. We examined whether rs4606, a single nucleotide polymorphism (SNP) in the 3' UTR of RGS2, was associated with GAD in an epidemiologic sample of adults exposed to the 2004 Florida Hurricanes.
- Publication
Depression and anxiety, 2009, Vol 26, Issue 4, p309
- ISSN
1520-6394
- Publication type
Journal Article
- DOI
10.1002/da.20528