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- Title
MicroRNA expression profiling is a potential diagnostic tool for thyroid cancer.
- Authors
Vriens, Menno R; Weng, Julie; Suh, Insoo; Huynh, Nhung; Guerrero, Marlon A; Shen, Wen T; Duh, Quan-Yang; Clark, Orlo H; Kebebew, Electron
- Abstract
Approximately 30% of fine-needle aspiration (FNA) biopsies of thyroid nodules are indeterminate or nondiagnostic. Recent studies suggest microRNA (miRNA, miR) is differentially expressed in malignant tumors and may have a role in carcinogenesis, including thyroid cancer. The authors therefore tested the hypothesis that miRNA expression analysis would identify putative markers that could distinguish benign from malignant thyroid neoplasms that are often indeterminate on FNA biopsy.
- Publication
Cancer, 2012, Vol 118, Issue 13, p3426
- ISSN
1097-0142
- Publication type
Journal Article
- DOI
10.1002/cncr.26587