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Title
Characterization of the gene structure, functional significance, and clinical application of RNF180, a novel gene in gastric cancer.
Authors
Cheung, Kin-Fai; Lam, Cleo N Y; Wu, Kaichun; Ng, Enders K O; Chong, Wilson W S; Cheng, Alfred S L; To, Ka-Fai; Fan, Daiming; Sung, Joseph J Y; Yu, Jun
Abstract
By using genome-wide methylation screening, the authors identified ring finger protein 180 (RNF180) as preferentially methylated in cancer. This study was undertaken to clarify its structure and functional role in gastric cancer.