Title

Isomerization of Functionalized Olefins by Using the Dinuclear Catalyst [Pd<sup>I</sup>(μ‐Br)(P<sup>t</sup>Bu<sub>3</sub>)]<sub>2</sub>: A Mechanistic Study.

Authors

Koley, Debasis; De, Sriman; Sivendran, Nardana; Gooßen, Lukas J.

Abstract

In a combined experimental and computational study, the isomerization activity of the dinuclear palladium(I) complex [PdI(μ‐Br)(PtBu3)]2 towards allyl arenes, esters, amides, ethers, and alcohols has been investigated. The calculated energy profiles for catalyst activation for two alternative dinuclear and mononuclear catalytic cycles, and for catalyst deactivation are in good agreement with the experimental results. Comparison of experimentally observed E/Z ratios at incomplete conversion with calculated kinetic selectivities revealed that a substantial amount of product must form via the dinuclear pathway, in which the isomerization is promoted cooperatively by two palladium centers. The dissociation barrier towards mononuclear Pd species is relatively high, and once the catalyst enters the energetically more favorable mononuclear pathway, only a low barrier has to be overcome towards irreversible deactivation.

Subjects

ISOMERIZATION; CATALYSTS; CATALYST poisoning; ALKENES; PALLADIUM; AMIDES

Publication

Chemistry - A European Journal, 2021, Vol 27, Issue 61, p15226

ISSN

0947-6539

Publication type

Academic Journal

DOI

10.1002/chem.202102554