Title

Efficient Synthesis of Phosphonamidates through One‐Pot Sequential Reactions of Phosphonites with Iodine and Amines.

Authors

Chen, Xunwei; Luo, Wenjun; Wang, Yanlin; Li, Zikang; Ma, Xiaorui; Peng, Ai‐Yun

Abstract

A one‐pot sequential strategy to construct phosphonamidates has been developed by generating phosphonites in situ from arylmagnesium bromides and triethyl phosphite followed by treatment with iodine and amines. A variety of phosphonamidates were obtained with good to excellent yields at room temperature from easily available materials.

Subjects

IODINE; AMINES; BROMIDES; PHOSPHONATES

Publication

Chemistry - A European Journal, 2020, Vol 26, Issue 63, p14474

ISSN

0947-6539

Publication type

Academic Journal

DOI

10.1002/chem.202002934