We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Interleukin-6 as an inflammatory mediator and target of therapy in chronic periaortitis.
- Authors
Vaglio, Augusto; Catanoso, Maria G; Spaggiari, Lucia; Magnani, Luca; Pipitone, Nicolò; Macchioni, Pierluigi; Pulsatelli, Lia; Nicastro, Maria; Becchi, Gabriella; Corradi, Domenico; Versari, Annibale; Boiardi, Luigi; Salvarani, Carlo
- Abstract
Chronic periaortitis (CP) usually responds to glucocorticoids, but some patients have glucocorticoid-refractory disease or contraindications to glucocorticoid therapy. This study was undertaken to evaluate treatment with the anti-interleukin-6 receptor (anti-IL-6R) antibody tocilizumab in 2 patients with CP, one with refractory disease and the other with contraindications to glucocorticoids, and to assess IL-6 levels in an additional cohort of patients with CP.
- Publication
Arthritis and rheumatism, 2013, Vol 65, Issue 9, p2469
- ISSN
1529-0131
- Publication type
Journal Article
- DOI
10.1002/art.38032