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- Title
Mitochondrial dysfunction increases inflammatory responsiveness to cytokines in normal human chondrocytes.
- Authors
Vaamonde-García, Carlos; Riveiro-Naveira, Romina R; Valcárcel-Ares, Marta N; Hermida-Carballo, Laura; Blanco, Francisco J; López-Armada, María J
- Abstract
Alterations in mitochondria play a key role in the pathogenesis of osteoarthritis (OA). The role of inflammation in the progression of OA has also acquired important new dimensions. This study was undertaken to evaluate the potential role of mitochondrial dysfunction in increasing the inflammatory response of normal human chondrocytes to cytokines.
- Publication
Arthritis and rheumatism, 2012, Vol 64, Issue 9, p2927
- ISSN
1529-0131
- Publication type
Journal Article
- DOI
10.1002/art.34508