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- Title
Multiple loci influencing hippocampal degeneration identified by genome scan.
- Authors
Melville, Scott A; Buros, Jacqueline; Parrado, Antonio R; Vardarajan, Badri; Logue, Mark W; Shen, Li; Risacher, Shannon L; Kim, Sungeun; Jun, Gyungah; DeCarli, Charles; Lunetta, Kathryn L; Baldwin, Clinton T; Saykin, Andrew J; Farrer, Lindsay A; Alzheimer's Disease Neuroimaging Initiative
- Abstract
Large genome-wide association studies (GWASs) have identified many novel genes influencing Alzheimer disease (AD) risk, but most of the genetic variance remains unexplained. We conducted a 2-stage GWAS for AD-related quantitative measures of hippocampal volume (HV), total cerebral volume (TCV), and white matter hyperintensities (WMH).
- Publication
Annals of neurology, 2012, Vol 72, Issue 1, p65
- ISSN
1531-8249
- Publication type
Journal Article
- DOI
10.1002/ana.23644