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Title
Cell-free hemoglobin-based blood substitutes and risk of myocardial infarction and death: a meta-analysis.
Authors
Natanson, Charles; Kern, Steven J; Lurie, Peter; Banks, Steven M; Wolfe, Sidney M
Abstract
Hemoglobin-based blood substitutes (HBBSs) are infusible oxygen-carrying liquids that have long shelf lives, have no need for refrigeration or cross-matching, and are ideal for treating hemorrhagic shock in remote settings. Some trials of HBBSs during the last decade have reported increased risks without clinical benefit.