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- Title
Comparison of angioplasty with infusion of tirofiban or abciximab and with implantation of sirolimus-eluting or uncoated stents for acute myocardial infarction: the MULTISTRATEGY randomized trial.
- Authors
Valgimigli, Marco; Campo, Gianluca; Percoco, Gianfranco; Bolognese, Leonardo; Vassanelli, Corrado; Colangelo, Salvatore; de Cesare, Nicoletta; Rodriguez, Alfredo E; Ferrario, Maurizio; Moreno, Raul; Piva, Tommaso; Sheiban, Imad; Pasquetto, Giampaolo; Prati, Francesco; Nazzaro, Marco S; Parrinello, Giovanni; Ferrari, Roberto; Multicentre Evaluation of Single High-Dose Bolus Tirofiban vs Abciximab With Sirolimus-Eluting Stent or Bare Metal Stent in Acute Myocardial Infarction Study (MULTISTRATEGY) Investigators
- Abstract
Abciximab infusion and uncoated-stent implantation is a complementary treatment strategy to reduce major adverse cardiac events in patients undergoing angioplasty for ST-segment elevation myocardial infarction (STEMI). It is uncertain whether there may be similar benefits in replacing abciximab with high-dose bolus tirofiban. Similarly, the use of drug-eluting stents in this patient population is currently discouraged because of conflicting results on efficacy reported in randomized trials and safety concerns reported by registries.
- Publication
JAMA, 2008, Vol 299, Issue 15, p1788
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.299.15.joc80026