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- Title
Sulfadoxine-pyrimethamine, chlorproguanil-dapsone, or chloroquine for the treatment of Plasmodium vivax malaria in Afghanistan and Pakistan: a randomized controlled trial.
- Authors
Leslie, Toby; Mayan, M Ismail; Hasan, M Anwar; Safi, M Hanif; Klinkenberg, Eveline; Whitty, Christopher J M; Rowland, Mark
- Abstract
In areas where Plasmodium falciparum and Plasmodium vivax coexist and treatments for the 2 species differ, misdiagnosis can lead to poor outcomes in either disease. A unified therapy effective against both species would reduce reliance on species-specific diagnosis, which in many areas is difficult to maintain. The antifolates are an important and affordable antimalarial class to which it is often assumed P vivax malaria is intrinsically resistant.
- Publication
JAMA, 2007, Vol 297, Issue 20, p2201
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.297.20.2201