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- Title
Somatic acquisition and signaling of TGFBR1*6A in cancer.
- Authors
Pasche, Boris; Knobloch, Thomas J; Bian, Yansong; Liu, Junjian; Phukan, Sharbani; Rosman, Diana; Kaklamani, Virginia; Baddi, Lisa; Siddiqui, Farida S; Frankel, Wendy; Prior, Thomas W; Schuller, David E; Agrawal, Amit; Lang, Jas; Dolan, M Eileen; Vokes, Everett E; Lane, William S; Huang, Chiang-Ching; Caldes, Trinidad; Di Cristofano, Antonio; Hampel, Heather; Nilsson, IngMarie; von Heijne, Gunnar; Fodde, Riccardo; Murty, V V V S; de la Chapelle, Albert; Weghorst, Christopher M
- Abstract
TGFBR1*6A is a common polymorphism of the type I transforming growth factor beta receptor (TGFBR1). Epidemiological studies suggest that TGFBR1*6A may act as a tumor susceptibility allele. How TGFBR1*6A contributes to cancer development is largely unknown.
- Publication
JAMA, 2005, Vol 294, Issue 13, p1634
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.294.13.1634