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- Title
Trends in the risks and benefits to patients with cancer participating in phase 1 clinical trials.
- Authors
Roberts, Thomas G, Jr; Goulart, Bernardo H; Squitieri, Lee; Stallings, Sarah C; Halpern, Elkan F; Chabner, Bruce A; Gazelle, G Scott; Finkelstein, Stan N; Clark, Jeffrey W
- Abstract
In the past, cancer patients entering phase 1 studies confronted the prospects of high risk and unlikely benefit. Over the last decade, cancer drugs under development have become more targeted, and the clinical research environment has become more scrutinized. The impact of these changes on the risks and benefits to patients who participate in phase 1 cancer trials is unknown.
- Publication
JAMA, 2004, Vol 292, Issue 17, p2130
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.292.17.2130