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- Title
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial.
- Authors
Steinhubl, Steven R; Berger, Peter B; Mann, J Tift, 3rd; Fry, Edward T A; DeLago, Augustin; Wilmer, Charles; Topol, Eric J; CREDO Investigators. Clopidogrel for the Reduction of Events During Observation
- Abstract
Following percutaneous coronary intervention (PCI), short-term clopidogrel therapy in addition to aspirin leads to greater protection from thrombotic complications than aspirin alone. However, the optimal duration of combination oral antiplatelet therapy is unknown. Also, although current clinical data suggest a benefit for beginning therapy with a clopidogrel loading dose prior to PCI, the practical application of this therapy has not been prospectively studied.
- Publication
JAMA, 2002, Vol 288, Issue 19, p2411
- ISSN
0098-7484
- Publication type
Journal Article
- DOI
10.1001/jama.288.19.2411