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- Title
Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension.
- Authors
Psaty, Bruce M; Smith, Nicholas L; Heckbert, Susan R; Vos, Hans L; Lemaitre, Rozenn N; Reiner, Alexander P; Siscovick, David S; Bis, Joshua; Lumley, Thomas; Longstreth, W T, Jr; Rosendaal, Frits R
- Abstract
A genetic variant in alpha-adducin has been associated with renal sodium reabsorption and salt-sensitive hypertension. Whether this genetic variant modifies the effect of diuretic therapy on the incidence of myocardial infarction (MI) and stroke is unknown.
- Publication
JAMA, 2002, Vol 287, Issue 13, p1680
- ISSN
0098-7484
- Publication type
Journal Article
- DOI
10.1001/jama.287.13.1680