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- Title
Effect of statin therapy on C-reactive protein levels: the pravastatin inflammation/CRP evaluation (PRINCE): a randomized trial and cohort study.
- Authors
Albert, M A; Danielson, E; Rifai, N; Ridker, P M; PRINCE Investigators
- Abstract
Plasma levels of the inflammatory biomarker C-reactive protein (CRP) predict cardiovascular risk, and retrospective studies suggest that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) may lower CRP in a manner largely independent of low-density lipoprotein cholesterol (LDL-C). However, prospective trial data directly evaluating this anti-inflammatory effect of statins are not available.
- Publication
JAMA, 2001, Vol 286, Issue 1, p64
- ISSN
0098-7484
- Publication type
Journal Article
- DOI
10.1001/jama.286.1.64