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- Title
Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs.
- Authors
Kris, Mark G; Johnson, Bruce E; Berry, Lynne D; Kwiatkowski, David J; Iafrate, A John; Wistuba, Ignacio I; Varella-Garcia, Marileila; Franklin, Wilbur A; Aronson, Samuel L; Su, Pei-Fang; Shyr, Yu; Camidge, D Ross; Sequist, Lecia V; Glisson, Bonnie S; Khuri, Fadlo R; Garon, Edward B; Pao, William; Rudin, Charles; Schiller, Joan; Haura, Eric B; Socinski, Mark; Shirai, Keisuke; Chen, Heidi; Giaccone, Giuseppe; Ladanyi, Marc; Kugler, Kelly; Minna, John D; Bunn, Paul A
- Abstract
Targeting oncogenic drivers (genomic alterations critical to cancer development and maintenance) has transformed the care of patients with lung adenocarcinomas. The Lung Cancer Mutation Consortium was formed to perform multiplexed assays testing adenocarcinomas of the lung for drivers in 10 genes to enable clinicians to select targeted treatments and enroll patients into clinical trials.
- Publication
JAMA, 2014, Vol 311, Issue 19, p1998
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.2014.3741