We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effect of testosterone supplementation with and without a dual 5α-reductase inhibitor on fat-free mass in men with suppressed testosterone production: a randomized controlled trial.
- Authors
Bhasin, Shalender; Travison, Thomas G; Storer, Thomas W; Lakshman, Kishore; Kaushik, Manas; Mazer, Norman A; Ngyuen, Ahn-Hoa; Davda, Maithili N; Jara, Hernan; Aakil, Adam; Anderson, Stephan; Knapp, Philip E; Hanka, Samson; Mohammed, Nurahmed; Daou, Pierre; Miciek, Renee; Ulloor, Jagadish; Zhang, Anqi; Brooks, Brad; Orwoll, Katie; Hede-Brierley, Leife; Eder, Richard; Elmi, Ayan; Bhasin, Geeta; Collins, Lauren; Singh, Ravinder; Basaria, Shehzad
- Abstract
Steroid 5α-reductase inhibitors are used to treat benign prostatic hyperplasia and androgenic alopecia, but the role of 5α-dihydrotestosterone (DHT) in mediating testosterone's effects on muscle, sexual function, erythropoiesis, and other androgen-dependent processes remains poorly understood.
- Publication
JAMA, 2012, Vol 307, Issue 9, p931
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.2012.227