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- Title
Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial.
- Authors
Bulger, Eileen M; May, Susanne; Brasel, Karen J; Schreiber, Martin; Kerby, Jeffrey D; Tisherman, Samuel A; Newgard, Craig; Slutsky, Arthur; Coimbra, Raul; Emerson, Scott; Minei, Joseph P; Bardarson, Berit; Kudenchuk, Peter; Baker, Andrew; Christenson, Jim; Idris, Ahamed; Davis, Daniel; Fabian, Timothy C; Aufderheide, Tom P; Callaway, Clifton; Williams, Carolyn; Banek, Jane; Vaillancourt, Christian; van Heest, Rardi; Sopko, George; Hata, J Steven; Hoyt, David B; ROC Investigators
- Abstract
Hypertonic fluids restore cerebral perfusion with reduced cerebral edema and modulate inflammatory response to reduce subsequent neuronal injury and thus have potential benefit in resuscitation of patients with traumatic brain injury (TBI).
- Publication
JAMA, 2010, Vol 304, Issue 13, p1455
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.2010.1405