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- Title
Epidermal growth factor gene functional polymorphism and the risk of hepatocellular carcinoma in patients with cirrhosis.
- Authors
Tanabe, Kenneth K; Lemoine, Antoinette; Finkelstein, Dianne M; Kawasaki, Hiroshi; Fujii, Tsutomu; Chung, Raymond T; Lauwers, Gregory Y; Kulu, Yakup; Muzikansky, Alona; Kuruppu, Darshini; Lanuti, Michael; Goodwin, Jonathan M; Azoulay, Daniel; Fuchs, Bryan C
- Abstract
Overexpression of epidermal growth factor (EGF) in the liver induces transformation to hepatocellular carcinoma in animal models. Polymorphisms in the EGF gene modulate EGF levels.
- Publication
JAMA, 2008, Vol 299, Issue 1, p53
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/jama.2007.65