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- Title
Altered cerebral gamma-aminobutyric acid type A-benzodiazepine receptor binding in panic disorder determined by [11C]flumazenil positron emission tomography.
- Authors
Hasler, Gregor; Nugent, Allison C; Carlson, Paul J; Carson, Richard E; Geraci, Marilla; Drevets, Wayne C
- Abstract
The benzodiazepine (BZD) receptor system has been implicated in the pathophysiologic mechanism of panic disorder (PD) by indirect evidence from pharmacological challenge studies and by direct evidence from single-photon emission computed tomography and positron emission tomography neuroimaging studies. However, the results of previous neuroimaging studies are in disagreement, possibly because of experimental design limitations related to sample size, matching between patients and controls, and confounding medication effects.
- Publication
Archives of general psychiatry, 2008, Vol 65, Issue 10, p1166
- ISSN
1538-3636
- Publication type
Journal Article
- DOI
10.1001/archpsyc.65.10.1166