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- Title
Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study.
- Authors
Perlis, Roy H; Purcell, Shaun; Fava, Maurizio; Fagerness, Jesen; Rush, A John; Trivedi, Madhukar H; Smoller, Jordan W
- Abstract
A small subset of patients with depression exhibit new or worsening suicidal thoughts or behavior during short-term treatment with antidepressants. Because cyclic adenosine monophosphate response element binding (CREB) protein has been implicated in both antidepressant mechanisms and suicide, the CREB1 gene represents a gene that possibly influences the risk for treatment-emergent suicidality.
- Publication
Archives of general psychiatry, 2007, Vol 64, Issue 6, p689
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.64.6.689