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- Title
Association of a functional polymorphism in the mu-opioid receptor gene with alcohol response and consumption in male rhesus macaques.
- Authors
Barr, Christina S; Schwandt, Melanie; Lindell, Stephen G; Chen, Scott A; Goldman, David; Suomi, Stephen J; Higley, J Dee; Heilig, Markus
- Abstract
Innate differences in opioid neurotransmission are hypothesized to influence abuse liability of alcohol. In humans, a variant of the mu-opioid receptor gene (OPRM1A118G) increases receptor affinity, alcohol-induced euphoria, and risk for alcohol use disorders.
- Publication
Archives of general psychiatry, 2007, Vol 64, Issue 3, p369
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.64.3.369