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- Title
Dysregulation of endogenous opioid emotion regulation circuitry in major depression in women.
- Authors
Kennedy, Susan E; Koeppe, Robert A; Young, Elizabeth A; Zubieta, Jon-Kar
- Abstract
There is extensive evidence implicating dysfunctions in stress responses and adaptation to stress in the pathophysiological mechanism of major depressive disorder (MDD) in humans. Endogenous opioid neurotransmission activating mu-opioid receptors is involved in stress and emotion regulatory processes and has been further implicated in MDD.
- Publication
Archives of general psychiatry, 2006, Vol 63, Issue 11, p1199
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.63.11.1199