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- Title
Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study.
- Authors
Bjelland, Ingvar; Tell, Grethe S; Vollset, Stein Emil; Refsum, Helga; Ueland, Per Magne
- Abstract
An association between depression and folate status has been demonstrated in clinical studies, whereas data are sparse on the relationship between depression and other components of 1-carbon metabolism such as vitamin B12, homocysteine, and the methylenetetrahydrofolate reductase 677C-->T polymorphism. The relationship between anxiety and these components is less well known. This study examined the associations between folate, total homocysteine, vitamin B12, and the methylenetetrahydrofolate reductase 677C-->T polymorphism, and anxiety and depression in a large population-based study.
- Publication
Archives of general psychiatry, 2003, Vol 60, Issue 6, p618
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.60.6.618