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- Title
Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance.
- Authors
Mulsant, Benoit H; Pollock, Bruce G; Kirshner, Margaret; Shen, Changyu; Dodge, Hiroko; Ganguli, Mary
- Abstract
Serum anticholinergic activity (SAA), as measured by a radioreceptor assay, quantifies a person's overall anticholinergic burden caused by all drugs and their metabolites. In several small geriatric patient groups, SAA has been associated with cognitive impairment or frank delirium. To our knowledge, there has not yet been any systematic study of the prevalence of SAA and its effect on cognition in a community-based population.
- Publication
Archives of general psychiatry, 2003, Vol 60, Issue 2, p198
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.60.2.198