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- Title
A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide.
- Authors
Mann, J J; Huang, Y Y; Underwood, M D; Kassir, S A; Oppenheim, S; Kelly, T M; Dwork, A J; Arango, V
- Abstract
Major depression and suicide are associated with fewer serotonin transporter (5-HTT) sites. The 5'-flanking promoter region of the 5-HTT gene has a biallelic insertion/deletion (5-HTTLPR). We assayed prefrontal cortical (PFC) 5-HTT binding in major depression and suicide and examine the relationship to the 5-HTTLPR allele.
- Publication
Archives of general psychiatry, 2000, Vol 57, Issue 8, p729
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.57.8.729