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- Title
A positron emission tomography study of quetiapine in schizophrenia: a preliminary finding of an antipsychotic effect with only transiently high dopamine D2 receptor occupancy.
- Authors
Kapur, S; Zipursky, R; Jones, C; Shammi, C S; Remington, G; Seeman, P
- Abstract
Quetiapine is a new atypical antipsychotic medication. As such, relatively little has been published regarding its in vivo effects at the dopamine type 2 (D2) and serotonin type 2a (5-HT2a) receptor systems. The following study was undertaken to explore these effects across the clinical dose range and relate this information to its clinical profile.
- Publication
Archives of general psychiatry, 2000, Vol 57, Issue 6, p553
- ISSN
0003-990X
- Publication type
Journal Article
- DOI
10.1001/archpsyc.57.6.553