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- Title
Molecular assay to detect metastatic head and neck squamous cell carcinoma.
- Authors
Becker, Marta T; Shores, Carol G; Yu, Kathy K; Yarbrough, Wendell G
- Abstract
The presence or absence of metastatic disease in cervical lymph nodes is the single most important determinant of therapy and prognosis for patients with head and neck squamous cell carcinoma (HNSCC). However, histologic examination fails to detect metastatic disease in a subset of neck dissection specimens. The accuracy of neck staging may be improved by the use of molecular techniques. Cytokeratins 5, 14, and 20 may be appropriate markers for HNSCC because they are expressed in HNSCC but not in lymphatic tissue.
- Publication
Archives of otolaryngology--head & neck surgery, 2004, Vol 130, Issue 1, p21
- ISSN
0886-4470
- Publication type
Journal Article
- DOI
10.1001/archotol.130.1.21