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Title
Suppression of thrombospondin-1 expression during uveal melanoma progression and its potential therapeutic utility.
Authors
Wang, Shoujian; Neekhra, Aneesh; Albert, Daniel M; Sorenson, Christine M; Sheibani, Nader
Abstract
To determine whether expression of thrombospondin-1 (TSP1), an endogenous inhibitor of angiogenesis, is downregulated during progression of uveal melanoma and whether administration of TSP1 and/or its antiangiogenic peptides attenuate tumor growth.
Publication
Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Vol 130, Issue 3, p336