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- Title
The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration.
- Authors
Yu, Chang-En; Bird, Thomas D; Bekris, Lynn M; Montine, Thomas J; Leverenz, James B; Steinbart, Ellen; Galloway, Nichole M; Feldman, Howard; Woltjer, Randall; Miller, Carol A; Wood, Elisabeth McCarty; Grossman, Murray; McCluskey, Leo; Clark, Christopher M; Neumann, Manuela; Danek, Adrian; Galasko, Douglas R; Arnold, Steven E; Chen-Plotkin, Alice; Karydas, Anna; Miller, Bruce L; Trojanowski, John Q; Lee, Virginia M-Y; Schellenberg, Gerard D; Van Deerlin, Vivianna M
- Abstract
Mutation in the progranulin gene (GRN) can cause frontotemporal dementia (FTD). However, it is unclear whether some rare FTD-related GRN variants are pathogenic and whether neurodegenerative disorders other than FTD can also be caused by GRN mutations.
- Publication
Archives of neurology, 2010, Vol 67, Issue 2, p161
- ISSN
1538-3687
- Publication type
Journal Article
- DOI
10.1001/archneurol.2009.328