We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease.
- Authors
Storch, Alexander; Jost, Wolfgang H; Vieregge, Peter; Spiegel, Jörg; Greulich, Wolfgang; Durner, Joachim; Müller, Thomas; Kupsch, Andreas; Henningsen, Henning; Oertel, Wolfgang H; Fuchs, Gerd; Kuhn, Wilfried; Niklowitz, Petra; Koch, Rainer; Herting, Birgit; Reichmann, Heinz; German Coenzyme Q(10) Study Group
- Abstract
Major hallmarks in the pathophysiology of Parkinson disease are cellular energy depletion and oxidative stress leading to cellular dysfunction and death. Coenzyme Q(10) (CoQ(10)) is an electron acceptor bridging mitochondrial complexes I and II/III and a potent antioxidant that consistently partially recovers the function of dopaminergic neurons.
- Publication
Archives of neurology, 2007, Vol 64, Issue 7, p938
- ISSN
0003-9942
- Publication type
Journal Article
- DOI
10.1001/archneur.64.7.nct60005