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- Title
The combined effect of paraoxonase promoter and coding region polymorphisms on the risk of arterial ischemic stroke among young adults.
- Authors
Voetsch, Barbara; Benke, Kelly S; Panhuysen, Carolien I; Damasceno, Benito P; Loscalzo, Joseph
- Abstract
Serum paraoxonase (PON1) is a high-density lipoprotein-associated esterase with antioxidant and antiatherogenic properties that has recently been implicated in the pathogenesis of cardiovascular disease. Interindividual variability in PON1 levels is determined by the Q192R and L55M coding region polymorphisms and by 2 recently described polymorphisms in the promoter of the PON1 gene, C(-107)T and G(-824)A.
- Publication
Archives of neurology, 2004, Vol 61, Issue 3, p351
- ISSN
0003-9942
- Publication type
Journal Article
- DOI
10.1001/archneur.61.3.351