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- Title
Prediction of neuropsychological impairment in multiple sclerosis: comparison of conventional magnetic resonance imaging measures of atrophy and lesion burden.
- Authors
Benedict, Ralph H B; Weinstock-Guttman, Bianca; Fishman, Inna; Sharma, Jitendra; Tjoa, Christopher W; Bakshi, Rohit
- Abstract
Cognition and magnetic resonance imaging correlations are well established in patients with multiple sclerosis (MS), but it is unclear whether lesion burden or atrophy accounts for most of the predictive variance. These indices have been directly compared in only a few studies. No such study included measurement of the third ventricle, which was strongly predictive of neuropsychological competence in the early literature. Furthermore, few studies accounted for the influence of age, premorbid intelligence, or depression.
- Publication
Archives of neurology, 2004, Vol 61, Issue 2, p226
- ISSN
0003-9942
- Publication type
Journal Article
- DOI
10.1001/archneur.61.2.226