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- Title
Opioid dose and drug-related mortality in patients with nonmalignant pain.
- Authors
Gomes, Tara; Mamdani, Muhammad M; Dhalla, Irfan A; Paterson, J Michael; Juurlink, David N
- Abstract
Opioids are widely prescribed for chronic nonmalignant pain, often at doses exceeding those recommended in clinical practice guidelines. However, the risk-benefit ratio of high-dose opioid therapy is not well characterized. The objective of this study was to characterize the relationship between opioid dose and opioid-related mortality.
- Publication
Archives of internal medicine, 2011, Vol 171, Issue 7, p686
- ISSN
1538-3679
- Publication type
Journal Article
- DOI
10.1001/archinternmed.2011.117