We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65,229 participants.
- Authors
Ray, Kausik K; Seshasai, Sreenivasa Rao Kondapally; Erqou, Sebhat; Sever, Peter; Jukema, J Wouter; Ford, Ian; Sattar, Naveed
- Abstract
Statins have been shown to reduce the risk of all-cause mortality among individuals with clinical history of coronary heart disease. However, it remains uncertain whether statins have similar mortality benefit in a high-risk primary prevention setting. Notably, all systematic reviews to date included trials that in part incorporated participants with prior cardiovascular disease (CVD) at baseline. Our objective was to reliably determine if statin therapy reduces all-cause mortality among intermediate to high-risk individuals without a history of CVD.
- Publication
Archives of internal medicine, 2010, Vol 170, Issue 12, p1024
- ISSN
1538-3679
- Publication type
Journal Article
- DOI
10.1001/archinternmed.2010.182