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- Title
Optimal level of oral anticoagulant therapy for the prevention of arterial thrombosis in patients with mechanical heart valve prostheses, atrial fibrillation, or myocardial infarction: a prospective study of 4202 patients.
- Authors
Torn, Marieke; Cannegieter, Suzanne C; Bollen, Ward L E M; van der Meer, Felix J M; van der Wall, Ernst E; Rosendaal, Frits R
- Abstract
Oral anticoagulant therapy is effective for the prevention of arterial thromboembolism in various patient groups. The increased risk of hemorrhage remains the major drawback to this therapy and is associated with the intensity of anticoagulation. Finding the optimal intensity at which the overall incidence rate of both bleeding and thromboembolic events is minimized represents a way to improve the safety of oral anticoagulant treatment.
- Publication
Archives of internal medicine, 2009, Vol 169, Issue 13, p1203
- ISSN
1538-3679
- Publication type
Journal Article
- DOI
10.1001/archinternmed.2009.176