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- Title
Tracing the flow of knowledge: geographic variability in the diffusion of prazosin use for the treatment of posttraumatic stress disorder nationally in the Department of Veterans Affairs.
- Authors
Harpaz-Rotem, Ilan; Rosenheck, Robert A
- Abstract
Passive diffusion of new medical innovations is an important mechanism by which knowledge transitions from research to clinical practice. Preliminary evidence has emerged about the effectiveness of the alpha(1)-adrenergic blocker prazosin hydrochloride in the treatment of nightmares and hyperarousal among patients with posttraumatic stress disorder (PTSD). This treatment has been neither widely accepted nor the subject of active dissemination efforts, and its efficacy was discovered in a discrete geographic location.
- Publication
Archives of general psychiatry, 2009, Vol 66, Issue 4, p417
- ISSN
1538-3636
- Publication type
Journal Article
- DOI
10.1001/archgenpsychiatry.2008.536