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- Title
Diagnostic accuracy of fractional flow reserve from anatomic CT angiography.
- Authors
Min, James K; Leipsic, Jonathon; Pencina, Michael J; Berman, Daniel S; Koo, Bon-Kwon; van Mieghem, Carlos; Erglis, Andrejs; Lin, Fay Y; Dunning, Allison M; Apruzzese, Patricia; Budoff, Matthew J; Cole, Jason H; Jaffer, Farouc A; Leon, Martin B; Malpeso, Jennifer; Mancini, G B John; Park, Seung-Jung; Schwartz, Robert S; Shaw, Leslee J; Mauri, Laura
- Abstract
Coronary computed tomographic (CT) angiography is a noninvasive anatomic test for diagnosis of coronary stenosis that does not determine whether a stenosis causes ischemia. In contrast, fractional flow reserve (FFR) is a physiologic measure of coronary stenosis expressing the amount of coronary flow still attainable despite the presence of a stenosis, but it requires an invasive procedure. Noninvasive FFR computed from CT (FFR(CT)) is a novel method for determining the physiologic significance of coronary artery disease (CAD), but its ability to identify ischemia has not been adequately examined to date.
- Publication
JAMA, 2012, Vol 308, Issue 12, p1237
- ISSN
1538-3598
- Publication type
Journal Article
- DOI
10.1001/2012.jama.11274