Works matching DNA topoisomerase II


Results: 1989
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    Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2171029
    By:
    • Farouk, Faten;
    • Elmaaty, Ayman Abo;
    • Elkamhawy, Ahmed;
    • Tawfik, Haytham O.;
    • Alnajjar, Radwan;
    • Abourehab, Mohammed A. S.;
    • Saleh, Mohamed A.;
    • Eldehna, Wagdy M.;
    • Al‐Karmalawy, Ahmed A.
    Publication type:
    Article
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    Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.

    Published in:
    Oncogene, 2003, v. 22, n. 52, p. 8448, doi. 10.1038/sj.onc.1207052
    By:
    • Whitmarsh, Ryan J.;
    • Saginario, Charles;
    • Zhuo, Ya;
    • Hilgenfeld, Eva;
    • Rappaport, Eric F.;
    • Megonigal, Maureen D.;
    • Carroll, Martin;
    • Liu, Mingli;
    • Osheroff, Neil;
    • Cheung, Nai-Kong V.;
    • Slater, Diana J.;
    • Ried, Thomas;
    • Knutsen, Turid;
    • Blair, Ian A.;
    • Felix, Carolyn A.
    Publication type:
    Article
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