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- Title
Levels of Calcitonin and Procalcitonin in Different Types of Thyroid Cancer in Kirkuk City-Iraq.
- Authors
Sulaiman, Maad Mohammed; Salih, Khalid Nafi; Raheef, Noor Falah; Alazzawy, Muhannad Abdullah
- Abstract
Thyroid cancer is the most common endocrine malignancy, accounting for 1.9% of all new malignant tumors. Thyroid cancer begins in the follicular cell of the thyroid gland. The aim of the study was to estimate the level of procalcitonin and thyroid tests in patients with different types of thyroid cancer. The number of thyroid cancer women under study were 40 women whose ages were between 25-75 years old were included in this cross-sectional study which carried out in Kirkuk city from the period of September 2016 to March 2017. These patients admitted to Kirkuk oncology center. The control group who were matched to the thyroid cancer patients studied, included 30 heathy individuals (blood donors). Blood was collected from patients and control for estimation of serum total TSH, T3, T4, FT3, FT4, and procalcitonin using immunefluorescent technique. The study showed that that the highest rate of increased PCT level was recorded among thyroid cancer patients comparing with the control group (25% v.s. 10%), the highest mean level of PCT was noticed among medullary thyroid cancer (8.22 ± 3.16 ng/ml) comparing with follicular and papillary thyroid cancer. The highest mean levels of TSH, T3 and T4 were noted among thyroid cancer patients (16.3± 4.22, 2.01 ± 0.55 and 144.1 ± 45.6) respectively comparing with the control group which showed the least means of TSH, T3 and T4 and with highly significant difference between the two groups. The study showed that the lowest mean of TSH was noted among MTC patients (0.88±0.61) comparing with FTC and PTC patients and the high means of FT3 and FT4 were noted among MTC patients (5.89±0.31and 19.25±2.48) respectively. Table 5 demonstrates that the lowest mean levels of FT3 noted among thyroid cancer patients comparing with the controls (2.99±10.91 v.s. 15.91±0.43). It was concluded that there was a highly significant relation procalcitonin and thyroid cancer specially medullary type.
- Subjects
KIRKUK (Iraq); IRAQ; THYROID cancer; CALCITONIN; MEDULLARY thyroid carcinoma; THYROID gland; CANCER
- Publication
Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 11, p4964
- ISSN
0976-0245
- Publication type
Academic Journal
- DOI
10.5958/0976-5506.2019.03936.6