This study focused on antifungal activity of alcoholic extracts of Boswellia gum onthe potent antifungal resistant opportunistic pathogen for humans, Aspergillus fumigatus. The antifungals used were: Terbinafine, Nystatin and Clotrimazol.Antimicrobial susceptibility testingof alcoholic gum extracts of Boswellia was done by well diffusion methodagainst the mold. Results showed that Boswellia extracts had the ability to inhibit fungal growth in vitro and the statistics revealed different inhibition zones gradually increased with the increasing in the concentration of theextract and that acetonic extract was more effective than ethanolic. Confirming the presence of saponins, volatile oils, terpensand phenolic compounds in acetonic extract withphenolic compounds in ethanolic extract.