Formulation and Evaluation of Acetic Acid Lotion for the Treatment of Wound Infection.

Al-Saedi, Fitua; Dakhil, Ibtihal Abdulkadhim; Hummod, Adil; QabasNather

Acetic acid has been used as a topical agent for healing wound infections. However, no studies have been done to formulate acetic acid based lotion and investigate its role in wound dressing. Therefore, the current workinvolved study the antibacterial activity of acetic acid against pathogenic bacteria associated with wound infections in vitro. In addition to formulate acetic acid lotion and study its role in the treatment of infected wounds, using mice model. The results show that acetic acid has antibacterial efficacy at different concentrations against pathogenic bacteria tested; Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter sp, Proteussp and Salmonella sp. The application of acetic acid based lotion on wound infected with P. aeruginosatwice a day for 6 days leads to prevent bacterial infection and treat wounds. Herein, we reveal that acetic acid lotion has potent antibacterialefficacy and plays a significant role in wound healing.

ACETIC acid; WOUND infections; PATHOGENIC bacteria; WOUND healing; BACTERIAL diseases

Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 11, p4827

0976-0245

Academic Journal

10.5958/0976-5506.2019.03914.7