Correlated level of interleukin (IL_10) with Allergic Rhinitis and Effect Study of Steroid in its Levels.

Saleh, Anas Ahmed; Al Majed Rasheed, Inas Abd

Background: the allergic rhinitis or hay fever, is the most common diseases or type of allergic, often associated with runny nose; nasal congestion; sneezing; sinus pressure and eye problems, that similar to cold, so in recent years allergic rhinitis increased in Iraqi population, because many important factors. The aims of the current study were to assessment (IL_10) in Patients serum and study the effect of Steroid in Its Levels.Patients and method: Patients' serums were collected form Salah Aldin General Hospital during period (November, 2018 - March, 2019) a total of 44 patients Suffering from Allergic rhinitis after diagnosis by physician ENT Specialist and control group included 32 (healthy person), the serum IL_10 levels that measured by the ELISA (Beckmancompany, USA) according to the manufacturer's protocols (IL_10 ELISA kits), All samples are detected in duplicate. Findings: Mean of age ± Standard division was (29.17 ± 7.65) compare to control 30.23 ± 8.90, high incidence allergic rhinitis in males 29(65.9%) than females 15(34.1%), also in control group; males18 (56.3 %) more than females14 (43.7 %); P<0.01. Also Results in of current study showed significant decreased levels of interleukin (10) in serum of Patients with allergic rhinitis as (8.21 ± 0.25), compare to control group (healthy persons) as (11.67 ± 0.33) differed significantly (P<0.01), but significant increased level of IL_10 (10.06 ± 0.23) in serum of Patients with allergic rhinitis who received gluococorticoid (steroid) Patients compare to Patients before received gluococorticoid (steroid), a differed significantly (P<0.01). Conclusion: high incidence Allergic Rhinitis in males than females. decreased level of (IL_10) in serum with allergic rhinitis but increased levels of IL-10 in Patients serum with allergic rhinitis who received gluococorticoid (steroid) Patients compare to Patients before received gluococorticoid (steroid).

ALLERGIC rhinitis; RHINORRHEA; STEROIDS; SNEEZING; ALLERGIES; ALLERGIC conjunctivitis

Indian Journal of Public Health Research & Development, 2019, Vol 10, Issue 11, p4780

0976-0245

Academic Journal

10.5958/0976-5506.2019.03906.8