Background: Prediabetes can increase the risk of cardiovascular disorders by 1.5 times higher than healthy people. Prevention efforts by changing lifestyles and losing weight provision of a chayote (sechium edule) instant. Objectives: The objectives of the study were to analyze the effect of chayote (sechium edule) instant on blood glucose of high school teachers of prediabetes. Method: This research was quasi-experimental study with pre-post control group design. The number of research samples was 25 for the intervention group, given provision of a chayote (sechium edule) instant (SE) and 25 for the intervention group were given nutritional education (NE) and 25 groups of nutritional education interventions and provision of a chayote (sechium edule) instant (NE SE) for 30 days. Normality test using Shapiro-Wilk, Statistical analysis using Wilcoxon Signed Ranks Test and multivariat of varians and Games-Howell test. Results: There were no difference of blood glucose before and after intervention in SE groups (p <0.05) in the provision of a chayote (sechium edule) instant intervention group decreased blood glucose levels by 6,32 ± 22,094 gr/dL; there were no difference of blood glucose before and after intervention in NE groups (p <0.05) in nutrition education training intervention group increased blood glucose levels by 10,08 ± 52,52 gr/dL; there were a difference in blood glucose before and after intervention in NE SE groups (p<0,05). in NE SE intervention group decreased blood glucose levels by 26,52 ± 23,63 gr/dL. There were a difference in blood glucose levels after intervention in third groups(p<0,05), and which has statistically significant differences in blood glucose levels were in the intervention NE group with intervention NE SE group. Conclusion: The administration of Nutrition education training and provision of a chayote (sechium edule) instant significantly decreased blood glucose levels in treatment group.