In this paper we study the oscillation criteria for the second order nonlinear differential equation with delay and advanced arguments of the form ([x(t) a(t)x(t - σ1) b(t)x(t σ2)]α)'' q(t)xβ(t - τ1) p(t)xγ(t τ2) = 0, t ≥ t0 where σ1, σ2, τ1 and τ2 are nonnegative constants and α, β and γ are the ratios of odd positive integers. Examples are provided to illustrate the main results.