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Title

Use of canakinumab in recurrent gout attacks in patients with multimorbidity — two clinical case reports.

Authors

Panejko, Anna; Skoczyńska, Marta; Gruszecka, Katarzyna

Abstract

Gout is a chronic autoinflammatory joint disease affecting an increasing proportion of the population. In treatment of flares we can use traditional anti-inflammatory drugs [nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine and glucocorticoids] and as a second-line biologic therapy with canakinumab which is a selective interleukin-1 beta (IL-1b) antagonist. This paper presents two clinical cases of patients treated with canakinumab due to lack of efficacy and contraindications to first-line drugs.

Subjects

JOINT diseases; ANTI-inflammatory agents; CONTRAINDICATIONS; BIOTHERAPY; INTERLEUKIN-1

Publication

Rheumatology Forum, 2024, Vol 10, Issue 4, p221

ISSN

2720-3921

Publication type

Academic Journal

DOI

10.5603/rf.98377

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