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- Title
Use of canakinumab in recurrent gout attacks in patients with multimorbidity — two clinical case reports.
- Authors
Panejko, Anna; Skoczyńska, Marta; Gruszecka, Katarzyna
- Abstract
Gout is a chronic autoinflammatory joint disease affecting an increasing proportion of the population. In treatment of flares we can use traditional anti-inflammatory drugs [nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine and glucocorticoids] and as a second-line biologic therapy with canakinumab which is a selective interleukin-1 beta (IL-1b) antagonist. This paper presents two clinical cases of patients treated with canakinumab due to lack of efficacy and contraindications to first-line drugs.
- Subjects
JOINT diseases; ANTI-inflammatory agents; CONTRAINDICATIONS; BIOTHERAPY; INTERLEUKIN-1
- Publication
Rheumatology Forum, 2024, Vol 10, Issue 4, p221
- ISSN
2720-3921
- Publication type
Academic Journal
- DOI
10.5603/rf.98377