Skin properties of itching without symptoms and associated factors among older adults in long-term care facilities.

Sari, Dianis Wulan; Takeo Minematsu; Mikako Yoshida; Aya Kitamura; Sanai Tomida; Masatoshi Abe; Uswatun Khasanah; Hiromi Sanada

Since itching without rash frequently among older adults' population, study about skin properties of itching without rash is important to develop prevention methods. Therefore, this study explored the skin properties related to itching without rash and the factors associated with them. A correlation, predictive designs study was conducted at Indonesian Long-term Care (LTC) facilities. Skin properties including skin barrier function and skin inflammation were examined by photographs (macroscopic and microscopic), stratum corneum (SC) hydration, skin Potential of Hydrogen (pH), and skin blotting. Itching experience and skincare behavior were obtained by questionnaire. The itching-related skin properties and associated factors were analyzed. A total of 405 residents participated in this study, with mean age was 74 years. The prevalence of itching on the whole body was 69.1%, and 50.3% of those manifesting itching on the left forearm involved itching without macroscopic abnormalities (itching without rash). SC hydration, skin pH, albumin and nerve growth factor ß (NGFß) were associated with itching without rash (p = 0.007, 0.012, < 0.001, and < 0.001, respectively). Additionally, factors associated with skin properties were age, sex, sun exposure experience, skincare, and hygiene care in the linear regression analysis. Measurement of skin biomarkers using skin blotting was a possible objective measurement of itching skin properties without rash regardless of the environmental condition.

ITCHING; ADULT care facilities; LONG-term care facilities; NURSING care facilities; OLDER people; NERVE growth factor; SUNSHINE; SKIN inflammation

Drug Discoveries & Therapeutics, 2023, Vol 17, Issue 3, p201

1881-7831

Academic Journal

10.5582/ddt.2022.01119