Works matching DE "PROTEIN kinase B"

Results: 2830

Podophyllotoxin Alleviates DSS-Induced Ulcerative Colitis via PI3K/AKT Pathway Activation.

Published in:

Physiological Research, 2025, v. 74, n. 2, p. 287, doi. 10.33549/physiolres.935487

By:

Ting LI;
Xiaoying WANG;
Jiawei WANG

Publication type:

Article

Downregulation of PHLDA2 promotes apoptosis and autophagy in endometrial cancer cells while inhibiting their proliferation and metastasis.

Published in:

European Journal of Gynaecological Oncology, 2025, v. 46, n. 5, p. 107, doi. 10.22514/ejgo.2025.071

By:

Meiping Guo;
Zhiying Wang;
Meiyan Lin

Publication type:

Article

Functional Equivalence of Insulin and IGF-1 in the In Vitro Culture of Chicken Primordial Germ Cells.

Published in:

Genes, 2025, v. 16, n. 5, p. 481, doi. 10.3390/genes16050481

By:

Liu, Xin;
Wu, Jun;
Peng, Yixiu;
Liu, Guangzheng;
Jin, Kai;
Niu, Yingjie;
Song, Jiuzhou;
Han, Wei;
Chen, Guohong;
Li, Bichun;
Zuo, Qisheng

Publication type:

Article

Regulation of FOXO3 subcellular localization by Kit ligand in the neonatal mouse ovary.

Published in:

Journal of Assisted Reproduction & Genetics, 2015, v. 32, n. 12, p. 1741, doi. 10.1007/s10815-015-0589-9

By:

Ezzati, M.;
Baker, Michael;
Saatcioglu, Hatice;
Aloisio, Gina;
Pena, Christopher;
Nakada, Yuji;
Cuevas, Ileana;
Carr, Bruce;
Castrillon, Diego

Publication type:

Article

Role of p38 MAPK, Akt and NFκB in renoprotective effects of nebivolol on renal ischemia-reperfusion injury in rats.

Published in:

Biotechnic & Histochemistry, 2023, v. 98, n. 6, p. 401, doi. 10.1080/10520295.2023.2212412

By:

Cavdar, Zahide;
Kocak, Ayse;
Ural, Cemre;
Afagh, Aysan;
Ersan, Sibel;
Ozbal, Seda;
Tatli, Merve;
Celik, Asli;
Arslan, Sevki;
Cavdar, Caner

Publication type:

Article

Homoharringtonine induces apoptosis of mammary carcinoma cells by inhibiting the AKT/mTOR signaling pathway.

Published in:

Veterinary & Comparative Oncology, 2024, v. 22, n. 1, p. 57, doi. 10.1111/vco.12948

By:

Zhang, Xue;
Mei, Chen;
Liang, Zhixuan;
Zhi, Yan;
Xu, Haojun;
Wang, Hongjun;
Dong, Hong

Publication type:

Article

Corrigendum: Addressing the Glycine‐Rich Loop of Protein Kinases by a Multi‐Facetted Interaction Network: Inhibition of PKA and a PKB Mimic.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 39, p. 8664, doi. 10.1002/chem.202002162

By:

Lauber, Birgit S.;
Hardegger, Leo A.;
Alam, Kazi A.;
Lund, Bjarte A.;
Dumele, Oliver;
Harder, Michael;
Kuhn, Bernd;
Engh, Richard A.;
Diederich, François

Publication type:

Article

A Chemical Epitope-Targeting Strategy for Protein Capture Agents: The Serine 474 Epitope of the Kinase Akt2.

Published in:

Angewandte Chemie, 2013, v. 125, n. 52, p. 14225, doi. 10.1002/ange.201305882

By:

Nag, Arundhati;
Das, Samir;
Yu, Mary Beth;
Deyle, Kaycie M.;
Millward, Steven W.;
Heath, James R.

Publication type:

Article

The pantothenic acid derivative dexpanthenol ameliorated doxorubicin-induced neurotoxicity via regulating AKT/CREB/BDNF and AKT/NRF2 signaling pathways.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10228-5

By:

Unlu, Melike Dogan;
Savran, Mehtap;
Imeci, Orhan;
Asci, Halil;
Ozmen, Ozlem

Publication type:

Article

Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade.

Published in:

Basic Research in Cardiology, 2015, v. 110, n. 2, p. 1, doi. 10.1007/s00395-015-0464-y

By:

Hernández-Reséndiz, Sauri;
Palma-Flores, Carlos;
los Santos, Sergio;
Román-Anguiano, Nadia;
Flores, Mirthala;
Peña, Aurora;
Flores, Pedro;
Fernández-G, Juan;
Coral-Vázquez, Ramón;
Zazueta, Cecilia

Publication type:

Article

Taurine protects dopaminergic neurons in paraquat-induced Parkinson's disease mouse model through PI3K/Akt signaling pathways.

Published in:

Amino Acids, 2022, v. 54, n. 1, p. 1, doi. 10.1007/s00726-021-03104-6

By:

Wang, Kaidong;
Zhang, Baofu;
Tian, Tian;
Zhang, Bingyang;
Shi, Ge;
Zhang, Chunhui;
Li, Guoliang;
Huang, Min

Publication type:

Article

Angiotensin-(3–7) alleviates isoprenaline-induced cardiac remodeling via attenuating cAMP-PKA and PI3K/Akt signaling pathways.

Published in:

Amino Acids, 2021, v. 53, n. 10, p. 1533, doi. 10.1007/s00726-021-03074-9

By:

Zhang, Yonglin;
Shang, Zhenglu;
Liu, Aijun

Publication type:

Article

GPR43 Suppresses Intestinal Tumor Growth by Modification of the Mammalian Target of Rapamycin Complex 1 Activity in ApcMin/+ Mice.

Published in:

2022

By:

Kong, Lingling;
Hoshi, Namiko;
Sui, Yunlong;
Yamada, Yasutaka;
Yoshida, Ryutaro;
Ooi, Makoto;
Tian, Zibin;
Kimura, Ikuo;
Kodama, Yuzo

Publication type:

journal article

Retraction: Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

Published in:: Biochemical Journal, 2025, v. 482, n. 7, p. 363, doi. 10.1042/BJ20030577_RET
Publication type:: Article

The insulin receptor family and protein kinase B (Akt) are activated in the heart by alkaline pH and α<sub>1</sub>-adrenergic receptors.

Published in:

Biochemical Journal, 2021, v. 478, n. 11, p. 2059, doi. 10.1042/BCJ20210144

By:

Meijles, Daniel N.;
Fuller, Stephen J.;
Cull, Joshua J.;
Alharbi, Hajed O.;
Cooper, Susanna T. E.;
Sugden, Peter H.;
Clerk, Angela

Publication type:

Article

Nebivolol Exerts Hepatoprotective Activity During CLP-Induced Sepsis by Modulating Oxidative Stress, Liver Regeneration, and AKT/MAPK Pathways in Rats.

Published in:

Stresses, 2024, v. 4, n. 4, p. 800, doi. 10.3390/stresses4040053

By:

Sabra, Rahma Tharwat;
Bekhit, Amany Abdlrehim;
Sabra, Nourhan Tharwat;
Abd El-Moeze, Nadia Ahmed;
Fathy, Moustafa

Publication type:

Article

DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat.

Published in:

Advanced Biology, 2023, v. 7, n. 5, p. 1, doi. 10.1002/adbi.202200160

By:

Urban, Lauren A.;
Li, Jiachun;
Gundogdu, Gokhan;
Trinh, Annie;
Shao, Hanjuan;
Nguyen, Travis;
Mauney, Joshua R.;
Downing, Timothy L.

Publication type:

Article

IL-22 activates the PI3K-AKT pathway to promote colorectal cancer cell proliferation and metastasis.

Published in:

Discover Oncology, 2024, v. 15, n. 1, p. 1, doi. 10.1007/s12672-024-01169-9

By:

Ruan, Hong-xun;
Qin, Xiao-ning;
Huang, Wei;
Lin, Lin

Publication type:

Article

Akt1 players promote PMA U937 cell line differentiation into macrophage-like cells.

Published in:

Arab Gulf Journal of Scientific Research, 2024, v. 42, n. 4, p. 1257, doi. 10.1108/AGJSR-12-2022-0317

By:

Bakheit, Halla Falih;
Taurin, Sebastien;
Elamin, Elwaleed Mohamed;
Bakhiet, Moiz

Publication type:

Article

SULFORAPHANE ATTENUATES HMGB1-MEDIATED ACTIVATION OF INFLAMMATORY PATHWAYS IN THE LIVER OF DIABETIC MICE AND SUPPRESSES FERROPTOSIS.

Published in:

Genetics & Applications, 2024, p. 75

By:

Vesna, Otašević;
Ana, Stančić;
Anđelija, Gudelj;
Nevena, Savić;
Milica, Markelić;
Ksenija, Veličković;
Vesna, Martinović;
Ilijana, Grigorov

Publication type:

Article

Loading necrostatin-1 composite bone cement inhibits necroptosis of bone tissue in rabbit.

Published in:

Regenerative Biomaterials, 2019, v. 6, n. 2, p. 113, doi. 10.1093/rb/rbz004

By:

Ji, Xiang;
Xu, Feng;
Dong, Guoling;
Jia, Chongzhe;
Jia, Pu;
Chen, Hao;
Tang, Hai

Publication type:

Article

茯砖茶调控脂噬干预小鼠非酒精性脂肪肝作用机制作用机制.

Published in:

Food Research & Development, 2024, v. 45, n. 19, p. 37, doi. 10.12161/j.issn.1005-6521.2024.19.006

By:

葛俊;
刘富林;
喻长红;
夏旭婷;
李霞;
施敏;
李琳莉

Publication type:

Article

Fraxetin suppresses reactive oxygen species‐dependent autophagy by the PI3K/Akt pathway to inhibit isoflurane‐induced neurotoxicity in hippocampal neuronal cells.

Published in:

Journal of Applied Toxicology, 2022, v. 42, n. 4, p. 617, doi. 10.1002/jat.4243

By:

Zhang, Tongyin;
Zhou, Botao;
Sun, Junyi;
Song, Jiangling;
Nie, Limin;
Zhu, Kairun

Publication type:

Article

Cadmium inhibits neural stem/progenitor cells proliferation via MitoROS‐dependent AKT/GSK‐3β/β‐catenin signaling pathway.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 12, p. 1998, doi. 10.1002/jat.4179

By:

Luo, Huan;
Song, Bo;
Xiong, Guiya;
Zhang, Bing;
Zuo, Zhenzi;
Zhou, Zhijun;
Chang, Xiuli

Publication type:

Article

Water‐soluble fraction of particulate matter <2.5 μm promoted lung epithelia cells apoptosis by regulating the expression of caveolin‐1 and Krüppel‐like factor 5.

Published in:

Journal of Applied Toxicology, 2021, v. 41, n. 3, p. 410, doi. 10.1002/jat.4052

By:

Wei, Wei;
Wang, Yuan;
Li, Min;
Yang, Ming

Publication type:

Article

Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 226, doi. 10.3390/jcm9010226

By:

Lin, Chih-Chung;
Lin, Wei-Ning;
Cho, Rou-Ling;
Yang, Chien-Chung;
Yeh, Yi-Cheng;
Hsiao, Li-Der;
Tseng, Hui-Ching;
Yang, Chuen-Mao

Publication type:

Article

Pathophysiological Implication of Fetuin-A Glycoprotein in the Development of Metabolic Disorders: A Concise Review.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 12, p. 2033, doi. 10.3390/jcm8122033

By:

Bourebaba, Lynda;
Marycz, Krzysztof

Publication type:

Article

Protein Kinase B and Extracellular Signal-Regulated Kinase Inactivation is Associated with Regorafenib-Induced Inhibition of Osteosarcoma Progression In Vitro and In Vivo.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 6, p. 900, doi. 10.3390/jcm8060900

By:

Pan, Po-Jung;
Liu, Yu-Chang;
Hsu, Fei-Ting

Publication type:

Article

Analgesic and Antidepressant Effects of Oltipraz on Neuropathic Pain in Mice by Modulating Microglial Activation.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 6, p. 890, doi. 10.3390/jcm8060890

By:

Díaz, Andrés Felipe;
Polo, Sara;
Gallardo, Núria;
Leánez, Sergi;
Pol, Olga

Publication type:

Article

The IGF1 Receptor Is Involved in Follicle-Stimulating Hormone Signaling in Porcine Neonatal Sertoli Cells.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 577, doi. 10.3390/jcm8050577

By:

Cannarella, Rossella;
Arato, Iva;
Condorelli, Rosita A.;
Luca, Giovanni;
Barbagallo, Federica;
Alamo, Angela;
Bellucci, Catia;
Lilli, Cinzia;
La Vignera, Sandro;
Calafiore, Riccardo;
Mancuso, Francesca;
Calogero, Aldo E.

Publication type:

Article

Advanced Evolution of Pathogenesis Concepts in Cardiomyopathies.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 4, p. 520, doi. 10.3390/jcm8040520

By:

Li, Chia-Jung;
Chen, Chien-Sheng;
Yiang, Giou-Teng;
Tsai, Andy Po-Yi;
Liao, Wan-Ting;
Wu, Meng-Yu

Publication type:

Article

Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 130, n. 2, p. 240, doi. 10.1111/bcpt.13696

By:

Zheng, Shaoyan;
Ma, Mingying;
Chen, Yanxia;
Li, Miaoxia

Publication type:

Article

Deletion or inhibition of prolyl oligopeptidase blocks lithium‐induced phosphorylation of GSK3b and Akt by activation of protein phosphatase 2A.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2021, v. 129, n. 4, p. 287, doi. 10.1111/bcpt.13632

By:

Myöhänen, Timo T.;
Mertens, Freke;
Norrbacka, Susanna;
Cui, Hengjing

Publication type:

Article

Sensitization of Hepatocellular Carcinoma Cells to Apo2 L/ TRAIL by a Novel Akt/ NF-κ B Signalling Inhibitor.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2014, v. 114, n. 6, p. 464, doi. 10.1111/bcpt.12190

By:

Omar, Hany A.;
Arafa, El‐Shaimaa A.;
Maghrabi, Ibrahim A.;
Weng, Jing‐Ru

Publication type:

Article

Coinhibitory Effects of Resveratrol- and Protopanaxadiol-Enriched Rice Seed Extracts Against Melanogenic Activities in Melan-a Cells.

Published in:

Plants (2223-7747), 2024, v. 13, n. 23, p. 3385, doi. 10.3390/plants13233385

By:

Monmai, Chaiwat;
Kuk, Yong-In;
Baek, So-Hyeon

Publication type:

Article

Rosemary as a Potential Source of Natural Antioxidants and Anticancer Agents: A Molecular Docking Study.

Published in:

Plants (2223-7747), 2024, v. 13, n. 1, p. 89, doi. 10.3390/plants13010089

By:

Bouammali, Haytham;
Zraibi, Linda;
Ziani, Imane;
Merzouki, Mohammed;
Bourassi, Lamiae;
Fraj, Elmehdi;
Challioui, Allal;
Azzaoui, Khalil;
Sabbahi, Rachid;
Hammouti, Belkheir;
Jodeh, Shehdeh;
Hassiba, Maryam;
Touzani, Rachid

Publication type:

Article

Resveratrol Inhibits Venezuelan Equine Encephalitis Virus Infection by Interfering with the AKT/GSK Pathway.

Published in:

Plants (2223-7747), 2021, v. 10, n. 2, p. 346, doi. 10.3390/plants10020346

By:

Lehman, Caitlin W.;
Kehn-Hall, Kylene;
Aggarwal, Megha;
Bracci, Nicole R.;
Pan, Han-Chi;
Panny, Lauren;
Lamb, Robert A.;
Lin, Shih-Chao;
Pintus, Francesca

Publication type:

Article

Effects of Extra Virgin Olive Oil Polyphenols on Beta-Cell Function and Survival.

Published in:

Plants (2223-7747), 2021, v. 10, n. 2, p. 286, doi. 10.3390/plants10020286

By:

Marrano, Nicola;
Spagnuolo, Rosaria;
Biondi, Giuseppina;
Cignarelli, Angelo;
Perrini, Sebastio;
Vincenti, Leonardo;
Laviola, Luigi;
Giorgino, Francesco;
Natalicchio, Annalisa;
Smeriglio, Antonella;
Pintus, Francesca

Publication type:

Article

EPHA2, a promising therapeutic target for hepatocellular carcinoma.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1910009

By:

Wang, Hao;
Qiu, Wei

Publication type:

Article

Targeting ganglioneuromas with mTOR inhibitors.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 1, p. 1, doi. 10.1080/23723556.2020.1856621

By:

Tao, Ting;
Shi, Hui;
Durbin, Adam D.;
Look, A. Thomas

Publication type:

Article

Potential targeted therapies for ovarian cancer beyond PARP inhibitors.

Published in:

European Journal of Gynaecological Oncology, 2025, v. 46, n. 3, p. 1, doi. 10.22514/ejgo.2025.030

By:

Sisman, Yagmur;
Høgdall, Dan;
Schnack, Tine Henrichsen;
Høgdall, Claus;
Høgdall, Estrid

Publication type:

Article

Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.

Published in:

Annals of Clinical & Translational Neurology, 2015, v. 2, n. 12, p. 1041, doi. 10.1002/acn3.254

By:

Carson, Robert P.;
Kelm, Nathaniel D.;
West, Kathryn L.;
Does, Mark D.;
Fu, Cary;
Weaver, Grace;
McBrier, Eleanor;
Parker, Brittany;
Grier, Mark D.;
Ess, Kevin C.

Publication type:

Article

投喂配合饲料和冰鱼对中华绒螯蟹生长、氨基酸代谢和胺类物质沉积的影响.

Published in:

Journal of Nanjing Agricultural University / Nanjuing Nongye Daxue Xuebao, 2021, v. 44, n. 5, p. 943, doi. 10.7685/jnau.202007048

By:

华皓坤;
刘文斌;
刘婷燕;
毛晶;
戴永军;
米海峰;
黄洋洋;
吴业阳;
蒋广震

Publication type:

Article

Rosuvastatin activates autophagy via inhibition of the Akt/mTOR axis in vascular smooth muscle cells.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 1, p. 117, doi. 10.4196/kjpp.24.284

By:

Seongpyo Lee;
Do-Hyung Lee;
Jin-Pyo Lee;
Joo-Hui Han

Publication type:

Article

Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 5, p. 367, doi. 10.4196/kjpp.2022.26.5.367

By:

Ye Seul Choi;
Hee Jeong Cho;
Hye Jin Jung

Publication type:

Article

NOX4/Src regulates ANP secretion through activating ERK1/2 and Akt/GATA4 signaling in beating rat hypoxic atria.

Published in:

Korean Journal of Physiology & Pharmacology, 2021, v. 25, n. 2, p. 159, doi. 10.4196/kjpp.2021.25.2.159

By:

Cheng-zhe Wu;
Xiang Li;
Lan Hong;
Zhuo-na Han;
Ying Liu;
Cheng-xi Wei;
Xun Cui

Publication type:

Article

Heat shock protein 90 inhibitor AUY922 attenuates platelet-derived growth factor-BB-induced migration and proliferation of vascular smooth muscle cells.

Published in:

Korean Journal of Physiology & Pharmacology, 2020, v. 24, n. 3, p. 241, doi. 10.4196/kjpp.2020.24.3.241

By:

Jisu Kim;
Kang Pa Lee;
Bom Sahn Kim;
Sang Ju Lee;
Byung Seok Moon;
Suji Baek

Publication type:

Article

Salvianolic acid B ameliorates psoriatic changes in imiquimod-induced psoriasis on BALB/c mice by inhibiting inflammatory and keratin markers via altering phosphatidylinositol-3-kinase/protein kinase B signaling pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2020, v. 24, n. 3, p. 213, doi. 10.4196/kjpp.2020.24.3.213

By:

Shoufan Wang;
Lihong Zhu;
Yihou Xu;
Zongbi Qin;
Aiqin Xu

Publication type:

Article

Hydroquinone suppresses IFN-β expression by targeting AKT/IRF3 pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2017, v. 21, n. 5, p. 547, doi. 10.4196/kjpp.2017.21.5.547

By:

Yong Kim;
Han Gyung Kim;
Sang Yun Han;
Deok Jeong;
Woo Seok Yang;
Jung-Il Kim;
Ji Hye Kim;
Young-Su Yi;
Jae Youl Cho

Publication type:

Article

Nafamostat mesilate promotes endothelium-dependent vasorelaxation via the Akt-eNOS dependent pathway.

Published in:

Korean Journal of Physiology & Pharmacology, 2016, v. 20, n. 5, p. 539, doi. 10.4196/kjpp.2016.20.5.539

By:

Sujeong Choi;
Hyon-Jo Kwon;
Hee-Jung Song;
Si Wan Choi;
Nagar, Harsha;
Shuyu Piao;
Saet-byel Jung;
Byeong Hwa Jeon;
Dong Woon Kim;
Cuk-Seong Kim

Publication type:

Article